Meyer is the daughter of Ronald Meyer, who currently serves as the vice chairman of NBCUniversal and was previously the president and CEO of Universal Studios, and his first wife Ellen. Her stepfather from her mother’s remarriage is Rabbi David Baron (head of the Temple Shalom for the Arts) and her stepmother from her father’s remarriage is Kelly Chapman. She got her start in jewelry making alongside her grandmother Edith Meyer, who began teaching Jennifer how to make enamel jewelry when she was six years old, Meyer studied psychology at Syracuse University then worked in public relations with fashion houses Giorgio Armani and Ralph Lauren.
Meyer met Tobey Maguire in 2003 while Maguire was shooting the movie Seabiscuit at Universal Studios, and became engaged in April 2006. Their daughter Ruby Sweetheart Maguire was born November 10, 2010 Ruby’s middle name comes from a childhood nickname of Meyer’s given to her by her grandmother, who died a few months before Ruby’s birth. Meyer and Maguire married on September 3, 2007, in Kona, Hawaii. Their second child, son Otis Tobias Maguire, was born on May 8, 2009. Meyer is Jewish and occasionally wears a Kabbalah bracelet placed on her “as a protection” by a friend of hers.